What is Peripheral Neuropathy?

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Peripheral neuropathy describes damage to the peripheral nervous system, which transmits information from the brain and spinal cord to every other part of the body.

In most cases, peripheral neuropathy is secondary to conditions including diabetes, lupus, rheumatoid arthritis, scleroderma, alcoholism, nutritional deficiencies, AIDS, or poisoning from heavy metals, chemotherapy, or various drugs.

Other causes include compression or entrapment (carpal tunnel syndrome), direct physical injury to a nerve (trauma), penetrated injuries, fractures or dislocated bones, pressure involving superficial nerves (ulna or radial) which can result from prolonged use of crutches or staying in same position, tumor, intraneural hemorrhage, exposure to cold, radiation or atherosclerosis.

It is a syndrome which includes symptoms of numbness, tingling, pricking sensations, sensitivity to touch, burning pain, and muscle weakness and atrophy of the arms and legs. The feet and legs are likely to be affected before the hands and arms.