Causes/Symptoms
Causes Canker sores are a common form of mouth ulcer. They occur in women more often than men. They may occur at any age, but usually first appear between the ages of 10 and 40.

Canker sores usually appear on the inner surface of the cheeks and lips, tongue, soft palate, and the base of the gums.

Canker sores can run in families. They may also be linked to problems with the body's immune (defense) system. The sores may occur after a mouth injury due to dental work, aggressive tooth cleaning, or biting the tongue or cheek.

Canker sores can be triggered by emotional stress, dietary deficiencies (especially iron, folic acid, or vitamin B-12), menstrual periods, hormonal changes, food allergies, and similar situations. They occur most commonly with viral infections. In some cases, the cause can not be identified.

Symptoms
The first symptom is usually a tingling or burning sensation that you feel before other symptoms develop.

The following symptoms may then occur:

Painful, red spot or bump that develops into an open ulcer
Center is colored white or yellow
Usually small (under 1 cm) but occasionally larger
Single bump or group of bumps (crops)
Sore may turn gray just before starting to heal

Less common symptoms include:
Fever
General discomfort or uneasiness (malaise)
Swollen lymph nodes
Pain decreases in 7 to 10 days, with complete healing in 1 to 3 weeks. Particularly large ulcers (greater than 1 cm in diameter) often take longer to heal (2 to 4 weeks). Occasionally, a severe occurrence may be accompanied by nonspecific symptoms of illness, such as fever. Canker sores often return.
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